Here’s a quick recap of the crypto landscape for Wednesday (December 10) as of 9:00 p.m. UTC.
Get the latest insights on Bitcoin, Ether and altcoins, along with a round-up of key cryptocurrencymarket news
Bitcoin and Ether price update
Bitcoin (BTC) was priced at US$92,516.67 down by 0.7 percent over 24 hours.
Chart via TradingView.
Bitcoin price performance, December 10, 2025.
The Bitcoin price reclaimed US$92,000 ahead of Wednesday’s US Federal Reserve meeting, with traders pricing in an interest rate cut, but holding back without signals of extended easing into 2026.
Bitcoin’s continued volatility and subdued options activity have dampened expectations for a typical year-end rally, with 30 day implied volatility easing to 49 percent and analysts seeing a December surge as unlikely.
ARK Invest CEO Cathie Wood remains bullish on Bitcoin in the longer term, arguing that the current pause does not signal a new bear cycle, and that Bitcoin is behaving as a resilient risk‑on asset.
In an email to the Investing News Network (INN), Farzam Ehsani, CEO of crypto exchange VALR, said he sees an overly optimistic market poised for a potential correction. He sees this move being driven by a “macro-political supercycle” of institutional and government actions rather than the traditional halving cycle.
Ray Youssef, CEO of NoOnes, called Wednesday’s Fed meeting outcome — the central bank cut rates as expected, but its dot plot signals just one more cut in 2026 with hawkish dissents.
“A more cautious or hawkish FOMC message would intensify pressure on already-thin sentiment in a market with a light order book and muted participation from retail and discretionary buyers,” he wrote to INN, adding that even modest selling pressure could trigger a retest of the mid-US$70,000s under these conditions.
Glassnode notes that Bitcoin is stuck in a fragile price range around US$92,700, held up by steady buying, but weighed down by big investors taking losses and long-term holders cashing in profits. Losses among holders are growing as time passes without a strong rebound, pushing more people to sell into small price upticks; combined with low spot activity and negative exchange-traded fund flows, this leaves the market highly sensitive to macro events.
Futures trading has shown caution, with little leveraged positioning for big moves, while options traders are buying short‑dated downside protection. Analysts project that Bitcoin could test higher levels near US$95,000 if sellers tire out, but staying below key support risks a pullback without fresh demand.
Meanwhile, traders have been driving the Ether/Bitcoin ratio up, signaling that capital is rotating from Bitcoin into altcoins, a dynamic that often precedes broader altcoin rallies. Bitcoin dominance is at 55.25.
Ether (ETH) was priced at US$3,362.98, up by 1 percent over the last 24 hours.
Altcoin price update
- XRP (XRP) was priced at US$2.07, down by 2.2 percent over 24 hours.
- Solana (SOL) was trading at US$138.48, down by 1.2 percent over 24 hours.
Crypto derivatives and market indicators
Bitcoin open interest rose 0.42 percent to US$59.47 billion, while Ether open interest stands at US$41.66 billion.
Bitcoin’s -0.002 percent funding rate reflects long pain, while a neutral relative strength index of 52.62 doesn’t indicate overbought or oversold extremes.
Today’s crypto news to know
Strategy writes to MSCI on DAT exclusion proposal
Bitcoin treasury pioneer Strategy (NASDAQ:MSTR) submitted a letter to MSCI’s Equity Index Committee on Tuesday (December 9), urging it to reject a proposal excluding digital asset treasury companies (DATs).
DATs are defined as firms with more than 50 percent of their assets in crypto.
“The proposal’s 50% rule arbitrarily singles out digital asset businesses for uniquely unfavorable treatment, while leaving untouched businesses in other industries (such as oil, timber, gold, media and entertainment, and real estate) that have similarly concentrated holdings in a single asset type,” the letter argues before concluding that the proposal “rests on a broad mischaracterization of DATs and would impose arbitrary, unworkable conditions that would stifle innovation, damage the reputation of MSCI’s indices, and conflict with national priorities.”
Genprex, the clinical-stage gene therapy company, is gearing up for an insightful showcase at the upcoming September investor and industry conferences. As the curtains rise on this exciting stage, Genprex plans to dazzle attendees with a glimpse into its cutting-edge gene therapies designed to revolutionize the treatment landscape for cancer and diabetes.
A Preview of the EventsMark your calendars for Genprex's participation in two key events this month. The stage is set, the spotlight is waiting – will you be there to witness the magic unfold?
The H.C. Wainwright 26th Annual Global Investment ConferenceFrom September 9 to 13, 2024, Genprex's President and Chief Executive Officer, Ryan Confer, will be taking center stage in the virtual realm. A presentation brimming with insights on the company's gene therapies for cancer and diabetes will be available on-demand from September 9 to 11, 2024. Confer's virtual presence promises to captivate audiences, offering a unique opportunity for investors to delve deep into Genprex's world of innovative treatments.
Chardan's 8th Annual Genetic Medicines ConferenceFor the in-person aficionados, the Westin Grand Central in New York, NY, will play host to Genprex's Senior Vice President of Intellectual Property and Licensing, Thomas Gallagher, on September 30 and October 1, 2024. Gallagher's presence promises engaging interactions with attendees, providing a firsthand glimpse into Genprex's remarkable strides in the field of genetic medicines.
Unveiling the Future of TreatmentWith a focus on developing life-altering therapies for cancer and diabetes, Genprex's innovative technologies are primed to usher in a new era of hope for patients with limited treatment options. Collaborating with esteemed institutions, the company is at the forefront of harnessing the power of gene therapy to cater to a broad patient base eagerly awaiting novel treatment approaches.
Genprex's cutting-edge oncology program utilizes the Oncoprex® Delivery System, a non-viral platform that encapsulates gene-expressing plasmids within lipid-based nanoparticles. This ingenious system, administered intravenously, propels tumor cells to express vital tumor suppressor proteins, effectively targeting deficiencies within the tumor.
The Company's lead product candidate, Reqorsa® Gene Therapy, is currently undergoing evaluation in clinical trials targeting Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC). With FDA Fast Track Designations under its belt, Genprex's lung cancer programs are making waves in the treatment landscape, redefining standards and ushering in a new dawn of hope for patients.
But the story doesn't end there. Genprex's foray into diabetes gene therapy unfolds a novel infusion process. By employing an AAV vector to deliver Pdx1 and MafA genes directly to the pancreas, the company's GPX-002 treatment promises transformative results. The treatment aims to rejuvenate and replenish beta cells, offering potential respite to patients grappling with Type 1 and Type 2 diabetes.
Embracing the Future TogetherAs Genprex paves the way for groundbreaking advancements in gene therapy, investors and stakeholders are invited to join this transformative journey. By engaging with the Company through press releases, industry updates, and social media channels, individuals can stay abreast of Genprex's trailblazing initiatives.
Excitement is in the air as Genprex prepares to enlighten, engage, and inspire at the upcoming conferences. Are you ready to be part of this extraordinary voyage into the future of gene therapies? The stage is set, the lights are dimming – it's time to witness history in the making.
OCC says banks can conduct riskless principal crypto trades
The Office of the Comptroller of the Currency (OCC) issued new guidance confirming that US national banks are allowed to execute riskless principal transactions involving crypto assets.
In these deals, a bank briefly takes the opposite side of a customer trade and immediately offsets it with a matching transaction, eliminating balance sheet exposure to the digital asset. The clarification is seen as a step toward giving regulated institutions more operational certainty when serving crypto-active clients. Banks conducting such activity must also comply with all existing consumer protection and anti-money-laundering rules.
Singapore leads new global crypto competitiveness index
Singapore has taken the top spot in Bybit and DL Research’s World Crypto Rankings 2025, edging out the US and Lithuania. Analysts credit the city-state’s strong licensing regime, high digital literacy and active institutional participation for pushing its total score to 7.5 out of 10. The report also highlights Singapore’s growing role in real-world asset tokenization, an area where market value has increased over 63 percent since early 2024 to reach US$25.7 billion.
The US remains closely behind with a score of 7.3, while Lithuania ranks third at 6.3.
US teachers union warns Senate against crypto market structure bill
The American Federation of Teachers (AFT) is urging the US Senate to throw out the Responsible Financial Innovation Act, arguing the proposal would undermine protections for retirement investors.
In a letter to Senate leadership, AFT President Randi Weingarten said the legislation could expose pension funds to “unsafe assets” and elevate risks tied to fraud and price instability in the crypto market.
The union fears that the bill’s tokenization provisions would allow companies to shift assets onto blockchain rails while sidestepping existing registration and disclosure rules. Weingarten argued that weaker oversight could ultimately threaten market stability and “lay the groundwork for the next financial crisis.”
Lummis comments on Responsible Financial Innovation Act
Speaking at the Blockchain Association Policy Summit on Tuesday, Wyoming Senator Cynthia Lummis, a member of the US Senate Banking Committee, said she anticipates that the markup hearing for the Responsible Financial Innovation Act will happen before Congress breaks for the holidays.
Lummis is a prominent proponent for addressing digital asset market structure in Congress.
Japan’s crypto regulation shift
Japan’s Financial Services Agency released a report from the Financial System Council’s Working Group on cryptocurrency regulation. The agency proposes moving the legal basis for crypto regulation from the Payment Services Act to the Financial Instruments and Exchange Act, the primary law governing securities markets, trading and disclosures.
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Securities Disclosure: I, Meagen Seatter, hold no direct investment interest in any company mentioned in this article.
Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.
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